01Profile Summary

I am a biophysics student at IISER Mohali working on membrane mechanics, plasma membrane vesicles, and quantitative image analysis. My research focuses on studying membrane morphology and mechanical properties using fluorescence microscopy and computational analysis tools. My current work involves quantitative analysis of giant plasma membrane vesicles (GPMVs) and biomimetic membrane systems.

02Education

BS–MS Dual DegreeBiology Major & Physics Minor
2022 — 2027
Indian Institute of Science Education and Research (IISER) Mohali

03Research

Current association
Master's Thesis Project Intern
May 2026 — Present
Max Planck Institute of Biophysics, Frankfurt | Supervisor: Dr. Uris Ros
Project: Micromechanics of Membrane Blebs in Regulated Necrotic Cell Death
  • Investigating time-dependent biophysical profiles (tension, rigidity, permeability) in giant plasma membrane vesicles (GPMVs) across regulated cell death channels.
Project Intern — Soft Matter Biophysics Lab
May 2023 — April 2026
IISER Mohali | Supervisor: Dr. Tripta Bhatia
  • Engineered micro-contour tracking protocols for biomimetic and plasma membrane vesicles.
  • Configured automated algorithm suites for geometric parameter parsing from brightfield and fluorescence microscopy datasets to isolate baseline membrane deviations.
Student Assistant — Bio-inspired Computation Lab
March 2024 — December 2025
University of Kiel, Germany (Remote) | Supervisor: Prof. Jan Steinkühler
  • Executed numerical simulations of DNA-based spring–mass systems modeled on structural multi-layered Worm-Like Chain networks.
  • Evaluated processing constraints of physical learning arrays across nonlinear dynamical multi-task behaviors.

04Publications

Papers · manuscripts · journal articles
Evolution of Vesicle Shape Parameters Based on A Deep-Learning Based Image Analysis Framework Over Extended Time Periods
T. Pandey, R. Kudawla, J.V.B.S, C. Devarakonda, A. Chatterjee, T. Bhatia
Under Revision
manuscript //
Directed evolution effectively selects for DNA-based physical reservoir computing networks
T. Pandey, P. Feketa, J. Steinkühler. (2026).
Neuromorphic Computing and Engineering (IOP).
doi // 10.1088/2634-4386/ae2cc3
Experimentally determined shapes of plasma membrane vesicles and PC/PC–cholesterol vesicles
H. Kaur, R. Kudawla, T. Pandey, T. Bhatia. (2025).
Journal of Physical Chemistry B (ACS).
doi // 10.1021/acs.jpcb.4c07431
Shape analysis of biomimetic and plasma membrane vesicles
R. Kudawla, H. Kaur, T. Pandey, T. Bhatia. (2024).
ChemSystemsChem (Wiley).
doi // 10.1002/syst.202400052

05Code & Tools

Code · open source · reproducible analysis
Python image analysis
VesEvol

VesEvol — Vesicle Evolution over Long Time. Image-analysis program for tracking and quantifying vesicle shape evolution over extended time periods.

Python Image Analysis Zenodo
10.5281/zenodo.22210498
Open-source toolkit
Vesicle Shape Analysis Toolkit

Open-source automation pipeline for micro-contour extraction, local curvature calculations, and quantitative mechanical analysis of biomimetic and plasma membrane vesicles.

Python Curvature Zenodo
10.5281/zenodo.17104430

06What I Know

Microscopy & Optics

Advanced optical microscopy alignment; manual GPMV isolation from cell frameworks; mammalian line management (HEK293T).

Image Segmentation

Deep-learning CNN image processing setups; automated geometric boundary parsing; custom manual validation UI tools.

Scientific Compute

Python (Numerical/Data stack), MATLAB, JavaScript. Programmatic structural pipeline engineering optimized for rapid image batch validation.

07Community

General Secretary and Hostel Representative
2025 — 2026
Student Representative Council (SRC), IISER Mohali